Job Details

Contract Senior CRA - Oncology (12-Month Contract, UK Remote)

(Outside IR35) | UK Remote | Phase III Solid Tumor Trial

We are partnering with a fast-growing, innovative biotechnology company advancing cutting-edge immuno-oncology therapies. As they scale their pivotal Phase III Solid Tumor study, they are seeking an experienced Contract Clinical Research Associate (CRA) to join their UK team.

This is a fantastic opportunity to work on a high-profile, late-phase oncology trial with a sponsor who values collaboration, innovation, and clinical excellence.

The Role

• Contract length: 12 months (with strong potential for extension)
  
  
• Therapeutic area: Oncology - Solid Tumors (Phase III)
  
  
• Coverage: 11 UK sites, supported by a team of 2 CRAs
  
  
• Location: Remote (UK-based), with routine travel to sites
  
  
• Engagement: Outside IR35

• Conduct routine on-site and remote monitoring (PSV, SIV, IMV, COV) across multiple UK sites.
  
  
• Ensure full compliance with ICH-GCP, study protocol, and sponsor SOPs.
  
  
• Maintain strong relationships with investigators and site staff to drive recruitment and data quality.
  
  
• Oversee SDV/SDR, query resolution, and timely site documentation updates in eTMF.
  
  
• Support audit/inspection readiness, corrective/preventive actions (CAPAs), and risk-based monitoring activities.

• 5+ years CRA experience, with a strong background in oncology trials (solid tumor preferred).
  
  
• Proven expertise in Phase II/III oncology studies within the UK.
  
  
• Ability to independently manage multiple sites and ensure timely study deliverables.
  
  
• Strong working knowledge of EDC systems (Medidata Rave preferred), CTMS, and eTMF.
  
  
• UK-based, with flexibility to travel across assigned sites.

• Join a sponsor-driven study rather than a CRO environment - your impact will be felt directly on trial outcomes.
  
  
• Contribute to a pivotal Phase III oncology program that has the potential to change treatment landscapes.
  
  
• Competitive outside IR35 contract rate with long-term engagement potential.